{"product_id":"phospho-lat-y220-rabbit-monoclonal-antibody-bs40034","title":"Phospho-LAT (Y220) Rabbit Monoclonal Antibody - BS40034","description":"\u003cp\u003ePhospho-LAT (Y220) Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40034-50, BS40034-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobμlin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobμlin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellμlar events such as mobilization of intracellμlar calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecμles.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human Mouse Rat\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\/IF, IP\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: 36 kDa phospho-tyrosine adaptor protein, LAT1, lat, pp36\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Phospho-LAT (Y220)\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500~1:2000 IHC 1:50~1:200 ICC\/IF 1:50~1:200 IP 1:30\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-LAT LAT (Y220) Antibody detects endogenous levels of total Phospho-LAT (Y220)\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 38kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O43561\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936875667635,"sku":"BS40034-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936875700403,"sku":"BS40034-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/phospho-lat-y220-rabbit-monoclonal-antibody-bs40034","provider":"AFSBio Inc.","version":"1.0","type":"link"}