{"product_id":"phospho-lrp6-thr1479-polyclonal-antibody-bs65913","title":"Phospho-LRP6 (Thr1479) Polyclonal Antibody - BS65913","description":"Phospho-LRP6 (Thr1479) Polyclonal Antibody\n\nSize: 100μl\n\nCatalogue Number: BS65913-100\n\nLead times: 1-2 weeks, if manufacturer has product in stock\n\nManufacturer\/Ship Location: China\n\nBackground: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt\/beta-catenin signaling cascade. Through its interaction with the Wnt\/beta-catenin signaling cascade this gene plays a role in the regμlation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regμlated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined\n\nCategory: Primary Antibody\n\nReactivity: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig\n\nHost: Rabbit\n\nApplications: FCM\n\nAlternate Names: LRP6 (Phospho-Thr1479), LRP6 (Phospho-T1479), p-LRP6 (Thr1479), p-LRP6 (T1479), ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6. \n\nClonality: Polyclonal\n\nConjugate: Unconjugated\n\nModification: Phosphorylation\n\nImmunogen: KLH conjugated Synthesised phosphopeptide derived from human LRP6 around the phosphorylation site of Thr1479:KG(p-T)YF \u003ccytoplasmic\u003e\n\nDilution: Flow-Cyt=0.2ug\/test\n\nPurification: affinity purified by Protein A\n\nSpecificity: Phospho-LRP6 (Thr1479) Polyclonal Antibody detects endogenous levels of LRP6 protein only when phosphorylated at Thr1479.\n\nMolecular Weight: 175kDa\n\nPathway: Regμlation of Microtubμle Dynamics, \n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nSwissProt: O75581\n\nProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\n\nResearch Use Only\u003c\/cytoplasmic\u003e","brand":"Bioworld","offers":[{"title":"100μl","offer_id":45936657891507,"sku":"BS65913-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/phospho-lrp6-thr1479-polyclonal-antibody-bs65913","provider":"AFSBio Inc.","version":"1.0","type":"link"}