{"product_id":"phospho-neurod1-ser274-polyclonal-antibody-bs65833","title":"phospho-NeuroD1 (Ser274) Polyclonal Antibody-BS65833","description":"\u003cp\u003ephospho-NeuroD1 (Ser274) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65833-50, BS65833-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13562\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Pig, Cow,Sheep,\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC-P=1:100-500\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -6°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6. 0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes;Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NeuroD1 (Ser274)) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~40 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: phospho-NeuroD1 (Ser274)Polyclonal Antibody detects endogenous levels of NeuroD1 protein only when phosphorylated at Y274.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: NeuroD1 (phospho S274); p-NeuroD1 (phospho S274); atonal; basic helix loop helix transcription factor; BETA 2; Beta cell E box transactivator 2; BETA2; BHF 1; BHF1; bHLHa3; class A basic helix loop helix protein 3; Class A basic helix-loop-helix protein 3; MODY 6; MODY6; NDF1_HUMAN; NEUROD; NeuroD1; Neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix loop helix protein NEUROD; NIDDM\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthesised acetylpeptide derived from human NeuroD1 around the acetylation site of Ser274:PL(p-S)PP\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939196866739,"sku":"BS65833-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939196899507,"sku":"BS65833-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_377e932b-3e87-44a9-99d3-bf17242f36e3.jpg?v=1704544905","url":"https:\/\/afsbio.com\/products\/phospho-neurod1-ser274-polyclonal-antibody-bs65833","provider":"AFSBio Inc.","version":"1.0","type":"link"}