{"product_id":"phospho-nrf2-ser40-monoclonal-antibody-bs65507","title":"phospho-Nrf2 (Ser40) Monoclonal Antibody - BS65507","description":"\u003cp\u003ephospho-Nrf2 (Ser40) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65507-50, BS65507-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regμlates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP) subfamily of basic \/leucine zipper (bZIP) transcription factors.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Nrf2 (phospho S40), p-Nrf2 (phospho S40), Nuclear factor-E2 related factor2, HEBP1, NF E2 related factor 2, NFE2 related factor 2, NFE2L2, Nrf 2, Nuclear factor erythroid 2 related factor 2, Nuclear factor erythroid derived 2 like 2, NF2L2_HUMAN.\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40:DF(p-S)QR\u003c\/p\u003e \n\n\u003cp\u003eDilution: IHC-P=1:100-500\u003cbr\u003e\nnot yet tested in other applications.\u003cbr\u003e\noptimal dilutions\/concentrations shoμld be determined by the end user.\u003c\/p\u003e\n\n\u003cp\u003ePurification: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-Nrf2 (Ser40) monoclonal antibody detects endogenous levels of Nrf2 protein only when phosphorylated at Ser40.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~100 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: AMPK Signaling Pathway,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q16236\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946359414963,"sku":"BS65507-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946359447731,"sku":"BS65507-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/phospho-nrf2-ser40-monoclonal-antibody-bs65507","provider":"AFSBio Inc.","version":"1.0","type":"link"}