{"product_id":"phospho-p53-ser15-polyclonal-antibody-bz16294","title":"Phospho-p53 (Ser15) Polyclonal Antibody-BZ16294","description":"\u003cp\u003ePhospho-p53 (Ser15) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16294-50, BZ16294-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P04637\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  ICC: 1\/100-1\/200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 44 kDa; Observed MW: 53 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-p53 in 293 lysates using Phospho-p53 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using p53 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-p53 in Hela cells using p53 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human TP53\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999932354739,"sku":"BZ16294-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999932387507,"sku":"BZ16294-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c34e767e-d7ac-4f2a-aaa1-8423d2a1496d.jpg?v=1706358294","url":"https:\/\/afsbio.com\/products\/phospho-p53-ser15-polyclonal-antibody-bz16294","provider":"AFSBio Inc.","version":"1.0","type":"link"}