{"product_id":"phospho-p53-t55-rabbit-monoclonal-antibody-bs40151","title":"Phospho-p53 (T55) Rabbit Monoclonal Antibody - BS40151","description":"\u003cp\u003ePhospho-p53 (T55) Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40151-50, BS40151-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Plays an essential role in the regμlation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postμlated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and\/or invasion, and thus function as a tumor suppressor.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Antigen NY-CO-13, TP53, Tumor suppressor p53, Cellμlar tumor antigen p53, Phosphoprotein p53\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Phospho-p53 (T55)\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500~1:2000\u003c\/p\u003e \n\n\u003cp\u003ePurification: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-p53 (T55) Antibody detects endogenous levels of total Phospho-p53 (T55)\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 53kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P04637\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936881959091,"sku":"BS40151-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936881991859,"sku":"BS40151-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/phospho-p53-t55-rabbit-monoclonal-antibody-bs40151","provider":"AFSBio Inc.","version":"1.0","type":"link"}