{"product_id":"phospho-pak1-2-3-ser144-ser141-ser154-monoclonal-antibody-mb11368","title":"Phospho-PAK1\/2\/3 (Ser144\/Ser141\/Ser154) Monoclonal Antibody-MB11368","description":"\u003cp\u003ePhospho-PAK1\/2\/3 (Ser144\/Ser141\/Ser154) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11368-50, MB11368-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O75914\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 62 kDa; Observed MW: 62 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of PAK1 \/PAK2 \/PAK3 in C6, 3T3, Hela lysates using Phospho-PAK1\/2\/3 antibody., Immunocytochemistry analysis of PAK1 \/PAK2 \/PAK3 in Hela using PAK1 \/PAK2 \/PAK3 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Phospho-PAK1\/2\/3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: PAK3; OPHN3; Serine\/threonine-protein kinase PAK 3; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser144 of human PAK1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004741517491,"sku":"MB11368-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004741550259,"sku":"MB11368-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fb9ffa95-bc5c-4323-80f6-6a633e064bab.jpg?v=1706445234","url":"https:\/\/afsbio.com\/products\/phospho-pak1-2-3-ser144-ser141-ser154-monoclonal-antibody-mb11368","provider":"AFSBio Inc.","version":"1.0","type":"link"}