{"product_id":"phospho-pim1-tyr309-polyclonal-antibody-bs65627","title":"Phospho-PIM1 (Tyr309) Polyclonal Antibody - BS65627","description":"\u003cp\u003ePhospho-PIM1 (Tyr309) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65627-50, BS65627-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the Ser\/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellμlar localization) resμlting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PIM1 (phospho Y309), PIM1 (phospho Tyr309), Oncogene PIM 1, Oncogene PIM1, PIM 1, Pim 1 kinase, Pim 1 oncogene, PIM, Pim2, PIM3, Proto oncogene serine\/threonine protein kinase Pim 1, Proviral integration site 1, Proviral integration site 2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthesised phosphopeptide derived from human PIM1 around the phosphorylation site of Tyr309\u003c\/p\u003e\n\n\u003cp\u003eDilution: Flow-Cyt=1ug\/Test\u003c\/p\u003e \n\n\u003cp\u003ePurification: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-PIM1 (Tyr309) Polyclonal Antibody detects endogenous levels of Phospho-PIM1 protein only when phosphorylated at Tyr309\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 45kD\u003c\/p\u003e\n\n\u003cp\u003ePathway: Examples of Crosstalk Between Post-translational Modifications,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P11309\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946360594611,"sku":"BS65627-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946360627379,"sku":"BS65627-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/phospho-pim1-tyr309-polyclonal-antibody-bs65627","provider":"AFSBio Inc.","version":"1.0","type":"link"}