{"product_id":"phospho-pkr-t446-rabbit-monoclonal-antibody-bs40095","title":"Phospho-PKR (T446) Rabbit Monoclonal Antibody-BS40095","description":"\u003cp\u003ePhospho-PKR (T446) Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40095-50, BS40095-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P19525\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003ePhospho-PKR (T446) Rabbit Monoclonal Antibody-BS40095\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IP, ChIP,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-PKR (T446) Antibody detects endogenous levels of total Phospho-PKR (T446)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 68kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of PKR phosphorylation expression in HeLa cell lysate treated with Calyculin A and TNF-alpha., Immunohistochemical analysis of paraffin-embedded human colon, using Phospho-PKR (T446) Antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: E2AK2; E2AK2; EIF2AK1; EIF2AK2; MGC126524; PKR p68 kinase; PKR; PRKR;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Phospho-PKR (T446)\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957268058291,"sku":"BS40095-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957268091059,"sku":"BS40095-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5d74d8bc-ead4-4965-be17-905e67dc0ce0.jpg?v=1705144241","url":"https:\/\/afsbio.com\/products\/phospho-pkr-t446-rabbit-monoclonal-antibody-bs40095","provider":"AFSBio Inc.","version":"1.0","type":"link"}