{"product_id":"phospho-raf1-s43-rabbit-monoclonal-antibody-bs40359","title":"Phospho-Raf1 (S43) Rabbit Monoclonal Antibody - BS40359","description":"\u003cp\u003ePhospho-Raf1 (S43) Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40359-50, BS40359-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine\/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human Mouse Rat\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: C-Raf, CRAF, Protein kinase raf 1, RAF1, Raf proto-oncogene serine\/threonine-protein kinase, kinase Raf1,\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Phospho-Raf1 (S43)\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-Raf1 (S43) Antibody detects endogenous levels of total Phospho-Raf1 (S43)\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 73kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P04049\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936895819955,"sku":"BS40359-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936895852723,"sku":"BS40359-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/phospho-raf1-s43-rabbit-monoclonal-antibody-bs40359","provider":"AFSBio Inc.","version":"1.0","type":"link"}