{"product_id":"phospho-rb-ser807-polyclonal-antibody-bz17056","title":"Phospho-Rb (Ser807) Polyclonal Antibody-BZ17056","description":"\u003cp\u003ePhospho-Rb (Ser807) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ17056-50, BZ17056-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P06400\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,IHC-F,IHC-P,ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4\/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK\/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Rb in CHO-K1, C6Lysates using Phospho-Rb antibody.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 106 kDa; Observed MW: 110 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser807 of human Rb\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42935422058675,"sku":"BZ17056-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42935422091443,"sku":"BZ17056-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5795d92e-568c-4bdd-943a-4635f2a3649d.jpg?v=1704370333","url":"https:\/\/afsbio.com\/products\/phospho-rb-ser807-polyclonal-antibody-bz17056","provider":"AFSBio Inc.","version":"1.0","type":"link"}