{"product_id":"phospho-smad5-s463-s465-rabbit-pab-ap1319","title":"Phospho-Smad5-S463\/S465 Rabbit pAb - AP1319","description":"\u003cp\u003ePhospho-Smad5-S463\/S465 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AP1319-20, AP1319-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eApplications: Phosphorylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 52kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4090\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q99717\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: DWFC; JV5-1; MADH5; Phospho-Smad5-S463\/S465\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, TGF-b-Smad Signaling Pathway, ESC Pluripotency and Differentiation, Stem Cells.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: SMAD5\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189430247603,"sku":"AP1319-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189430280371,"sku":"AP1319-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_cbea3b06-6fae-4ae8-a125-03e5ea457b4a.png?v=1766427037","url":"https:\/\/afsbio.com\/products\/phospho-smad5-s463-s465-rabbit-pab-ap1319","provider":"AFSBio Inc.","version":"1.0","type":"link"}