{"product_id":"phospho-taok1-2-3-ser181-ser181-ser177-monoclonal-antibody-mb11897","title":"Phospho-TAOK1\/2\/3 (Ser181\/Ser181\/Ser177) Monoclonal Antibody-MB11897","description":"\u003cp\u003ePhospho-TAOK1\/2\/3 (Ser181\/Ser181\/Ser177) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB11897-50, MB11897-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q7L7X3\/Q9H2K8\/Q9UL54\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Serine\/threonine-protein kinase involved in various processes such as p38\/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38\/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38\/MAPK14. In response to DNA damage, involved in the G2\/M transition DNA damage checkpoint by activating the p38\/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-TAOK1\/TAOK2 \/TAOK3 in 3T3 lysates using Phospho-TAOK1\/2\/3 antibody., Western blot analysis of TAOK1 \/TAOK2 \/TAOK3 in Hela, A549, HL-60, U2OS, C6 lysates using TAOK1 \/TAOK2 \/TAOK3 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using TAOK1 \/TAOK2 \/TAOK3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: DPK; JIK; hKFC-A; MAP3K18\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004749119667,"sku":"MB11897-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004749152435,"sku":"MB11897-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e45124ce-f1f6-4bb2-874b-b2a442af2d7c.jpg?v=1706445505","url":"https:\/\/afsbio.com\/products\/phospho-taok1-2-3-ser181-ser181-ser177-monoclonal-antibody-mb11897","provider":"AFSBio Inc.","version":"1.0","type":"link"}