{"product_id":"phospho-trkb-y817-rabbit-monoclonal-antibody-bs40184","title":"Phospho-TrkB (Y817) Rabbit Monoclonal Antibody-BS40184","description":"\u003cp\u003ePhospho-TrkB (Y817) Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40184-50, BS40184-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q16620\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003ePhospho-TrkB (Y817) Rabbit Monoclonal Antibody-BS40184\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC ICC\/IF, IP,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500~1:1000 IHC 1:50~1:100 ICC\/IF 1:50~1:100 IP 1:30\u003c\/p\u003e\n\n\u003cp\u003eBackground: The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-TrkB (Y817) Antibody detects endogenous levels of Phospho-TrkB (Y817)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 140kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Phospho-TrkB (Y817) expression in SH-SY5Y cell lysate treated with BDNF., Immunohistochemical analysis of paraffin-embedded mouse brain cancer, using Phospho-TrkB (Y817) Antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: NTRK2; gp145-TrkB; Trk-B; TRKB; Tropomyosin-related kinase B; TrkB tyrosine kinase; Tyrosine kinase receptor B;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human Phospho-TrkB (Y817)\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957279068339,"sku":"BS40184-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957279101107,"sku":"BS40184-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c96de792-acec-409b-bb07-f38a750ccbc8.jpg?v=1705144338","url":"https:\/\/afsbio.com\/products\/phospho-trkb-y817-rabbit-monoclonal-antibody-bs40184","provider":"AFSBio Inc.","version":"1.0","type":"link"}