{"product_id":"phx2a-polyclonal-antibody-bt-ap13003","title":"PHX2A Polyclonal Antibody - BT-AP13003","description":"\u003cp\u003ePHX2A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13003-20, BT-AP13003-50, BT-AP13003-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PHOX2A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Paired mesoderm homeobox protein 2A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O14813; Mouse: Q62066; Rat: Q62782\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Paired mesoderm homeobox protein 2A;ARIX1 homeodomain protein;Aristaless homeobox protein homolog;Paired-like homeobox 2A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 401\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239285940403,"sku":"BT-AP13003-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239285973171,"sku":"BT-AP13003-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239286005939,"sku":"BT-AP13003-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1d446149-756e-48f4-a654-19b0153a0546.png?v=1769392538","url":"https:\/\/afsbio.com\/products\/phx2a-polyclonal-antibody-bt-ap13003","provider":"AFSBio Inc.","version":"1.0","type":"link"}