{"product_id":"phx2b-polyclonal-antibody-bt-ap13004","title":"PHX2B Polyclonal Antibody - BT-AP13004","description":"\u003cp\u003ePHX2B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13004-20, BT-AP13004-50, BT-AP13004-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PHOX2B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Paired mesoderm homeobox protein 2B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q99453; Mouse: O35690\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Paired mesoderm homeobox protein 2B;Neuroblastoma Phox;NBPhox;PHOX2B homeodomain protein;Paired-like homeobox 2B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8929\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239286038707,"sku":"BT-AP13004-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239286071475,"sku":"BT-AP13004-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239286104243,"sku":"BT-AP13004-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_92f95e46-e9e0-454a-b553-9a2dcb8ff0ed.png?v=1769392540","url":"https:\/\/afsbio.com\/products\/phx2b-polyclonal-antibody-bt-ap13004","provider":"AFSBio Inc.","version":"1.0","type":"link"}