{"product_id":"pias-3-polyclonal-antibody-ra28751","title":"PIAS 3 Polyclonal Antibody - RA28751","description":"\u003cp\u003ePIAS 3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28751-50, RA28751-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: protein inhibitor of activated STAT 3 (PIAS3) Homo sapiens This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription) ] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier) -E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: PIAS3; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 10401\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 68\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9Y6X2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122362376371,"sku":"RA28751-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122362409139,"sku":"RA28751-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_71a8b3a7-ec10-47da-bf45-23bf2834e2c4.png?v=1773348013","url":"https:\/\/afsbio.com\/products\/pias-3-polyclonal-antibody-ra28751","provider":"AFSBio Inc.","version":"1.0","type":"link"}