{"product_id":"pidd-polyclonal-antibody-e-ab-63806","title":"PIDD Polyclonal Antibody - E-AB-63806","description":"\u003cp\u003ePIDD Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63806-60, E-AB-63806-120, E-AB-63806-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PIDD\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PIDD1; LRDD; PIDD\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9HB75\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PIDD (NP_665893.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:1000   IHC \t1:50-1:200   IF \t1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33kDa\/37kDa\/58kDa\/66kDa\/82kDa\/97kDa\/99kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100-110kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146299965619,"sku":"E-AB-63806-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146299998387,"sku":"E-AB-63806-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146300031155,"sku":"E-AB-63806-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f11b3148-5855-4028-a5cc-2c3b411eeeb3.png?v=1710293268","url":"https:\/\/afsbio.com\/products\/pidd-polyclonal-antibody-e-ab-63806","provider":"AFSBio Inc.","version":"1.0","type":"link"}