{"product_id":"pik3c2a-polyclonal-antibody-bs71277","title":"PIK3C2A Polyclonal Antibody-BS71277","description":"\u003cp\u003ePIK3C2A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS71277-50, BS71277-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O00443\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000  IHC\t1:50 - 1:200  IF\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PIK3C2A polyclonal antibody detects endogenous levels of PIK3C2A protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 191 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cells, using PIK3C2A antibody., Immunohistochemistry of paraffin-embedded mouse heart using PIK3C2A antibody at dilution of 1:100 (x40 lens)., Immunoprecipitation analysis of 200ug extracts of HeLa cells, using 3 ug PIK3C2A antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CPK; PI3-K-C2A; PI3-K-C2(ALPHA);\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein of human PIK3C2A.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997584003251,"sku":"BS71277-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997584036019,"sku":"BS71277-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_67fdec37-dddf-4aae-94d2-3b4840d0b361.jpg?v=1706270726","url":"https:\/\/afsbio.com\/products\/pik3c2a-polyclonal-antibody-bs71277","provider":"AFSBio Inc.","version":"1.0","type":"link"}