{"product_id":"pik3c3-polyclonal-antibody-e-ab-67600","title":"PIK3C3 Polyclonal Antibody - E-AB-67600","description":"\u003cp\u003ePIK3C3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67600-120, E-AB-67600-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PIK3C3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PIK3C3; VPS34; Vps34; hVps34\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8NEB9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphatidylinositol 3-kinase catalytic subunit type 3is anenzymethat in humans is encoded by thePIK3C3gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human PIK3C3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 101kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"120μL","offer_id":43149050806451,"sku":"E-AB-67600-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43149050839219,"sku":"E-AB-67600-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7891ab57-5b4a-4e6f-8e7f-0f79e59c2afa.png?v=1710339313","url":"https:\/\/afsbio.com\/products\/pik3c3-polyclonal-antibody-e-ab-67600","provider":"AFSBio Inc.","version":"1.0","type":"link"}