{"product_id":"pjvk-rabbit-polyclonal-antibody-es14099","title":"PJVK Rabbit Polyclonal Antibody - ES14099","description":"\u003cp\u003ePJVK Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES14099-50, ES14099-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the gasdermin family, a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59). [provided by RefSeq, Dec 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Pejvakin (Autosomal recessive deafness type 59 protein)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human PJVK AA range: 69-119\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: PJVK\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of PJVK at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.23% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 38kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Disease: Defects in PJVK are the cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59) [MIM: 610220]. DFNB59 is a form of sensorineural hearing impairment with absent or severely abnormal auditory brainstem response but normal otoacoustic emissions (auditory neuropathy or auditory dys-synchrony). Auditory neuropathies result from a lesion in the area including the inner hair cells, connections between the inner hair cells and the cochlear branch of the auditory nerve, the auditory nerve itself and auditory pathways of the brainstem\u003cbr\u003e\nFunction: Essential in the activity of auditory pathway neurons\u003cbr\u003e\nMiscellaneous: 'Pejvakin' means 'echo' in Persian\u003cbr\u003e\nSimilarity: Belongs to the gasdermin family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Peroxisome membrane Cell projection, cilium Associates with the peroxisomal membrane, it is unclear whether it is embedded or just associated with the peroxisomal membrane Localizes to ciliary rootlet\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: PJVK DFNB59\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: PJVK\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 381375\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q0ZLH2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315122196659,"sku":"ES14099-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315122229427,"sku":"ES14099-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/pjvk-rabbit-polyclonal-antibody-es14099","provider":"AFSBio Inc.","version":"1.0","type":"link"}