{"product_id":"pka-iβ-reg-rabbit-pab-es3219","title":"PKA Iβ reg rabbit pAb - ES3219","description":"\u003cp\u003ePKA Iβ reg rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3219-50, ES3219-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PRKAR1B; cAMP-dependent protein kinase type I-beta regulatory subunit\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human KAP1. AA range:106-155\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 43kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5575\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P31321\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202122408115,"sku":"ES3219-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202122440883,"sku":"ES3219-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_97835ebe-e4db-4d23-99a7-7f85a554c8bc.png?v=1767122429","url":"https:\/\/afsbio.com\/products\/pka-i%ce%b2-reg-rabbit-pab-es3219","provider":"AFSBio Inc.","version":"1.0","type":"link"}