{"product_id":"pkcμ-polyclonal-antibody-bs91086","title":"PKCμ Polyclonal Antibody-BS91086","description":"\u003cp\u003ePKCμ Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS91086-50, BS91086-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q15139(Human) Q62101(Mouse) Q9WTQ1(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14\/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of PKC mu on different cell lysate using anti-PKC mu antibody at 1\/1,000 dilution. Positive control： Lane 1: Hela Lane 2: Mouse kidney Lane 3: PC12\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 102 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: PKCμ polyclonal antibody detects endogenous levels of PKCμ protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: PRKD1, PKD, PKD1, PRKCM, KPCD1, nPKC D1, nPKC mu, nPKC-D1, nPKC-mu, nPKCD1, nPKCmu, PKC, PKC MU, PKCM, PKCmu, PKD 1, PKD, PKD1, PRKCM, PRKD 1, Prkd1, Protein kinase C mu, Protein kinase C mu type, Protein kinase D, Protein kinase D1, Serine\/threonine protein kinase D1, Serine\/threonine-protein kinase D1,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939205222579,"sku":"BS91086-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939205255347,"sku":"BS91086-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c1c70955-dfbd-47ef-a959-6985b19c8819.jpg?v=1704545071","url":"https:\/\/afsbio.com\/products\/pkc%ce%bc-polyclonal-antibody-bs91086","provider":"AFSBio Inc.","version":"1.0","type":"link"}