{"product_id":"pkc-ζ-phospho-thr410-polyclonal-antibody-ra28817","title":"PKC ζ (phospho Thr410) Polyclonal Antibody - RA28817","description":"\u003cp\u003ePKC ζ (phospho Thr410) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28817-50, RA28817-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: protein kinase C zeta (PRKCZ) Homo sapiens Protein kinase C (PKC) zeta is a member of the PKC family of serine\/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5590\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 70\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q05513\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122366341299,"sku":"RA28817-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122366374067,"sku":"RA28817-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_391f0b02-779e-4e82-8528-91020ecb5b9e.png?v=1773348051","url":"https:\/\/afsbio.com\/products\/pkc-%ce%b6-phospho-thr410-polyclonal-antibody-ra28817","provider":"AFSBio Inc.","version":"1.0","type":"link"}