{"product_id":"pkm1-specific-polyclonal-antibody-e-ab-92126","title":"PKM1-specific Polyclonal Antibody - E-AB-92126","description":"\u003cp\u003ePKM1-specific Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92126-60, E-AB-92126-120, E-AB-92126-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PKM1-specific\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1;\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P14618\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human PKM1-specific\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 56kDa\/57kDa\/58kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 58kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146626859187,"sku":"E-AB-92126-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146626891955,"sku":"E-AB-92126-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146626924723,"sku":"E-AB-92126-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_317aefaa-872e-40d7-b944-950d76795654.png?v=1710298765","url":"https:\/\/afsbio.com\/products\/pkm1-specific-polyclonal-antibody-e-ab-92126","provider":"AFSBio Inc.","version":"1.0","type":"link"}