{"product_id":"pkm2-polyclonal-antibody-bt-ap07236","title":"PKM2 Polyclonal Antibody - BT-AP07236","description":"\u003cp\u003ePKM2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07236-20, BT-AP07236-50, BT-AP07236-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: PKM encodes a protein involved in glycolysis. Pyruvate kinase, muscleprovided by is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. Pyruvate kinase, muscleprovided by has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. Pyruvate kinase, muscleprovided by has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of pyruvate kinase, muscleprovided by in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PKM\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PKM2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 57937\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P14618; Mouse: P52480; Rat: P11980\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1\/M2; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2\/3; Pyruvate kinase muscle isozyme; Thyr\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5315; Mouse: 18746; Rat: 25630\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239842144435,"sku":"BT-AP07236-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239842177203,"sku":"BT-AP07236-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239842209971,"sku":"BT-AP07236-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0d4d9e5d-813f-49eb-b577-a3f231dbe8a0.png?v=1769399850","url":"https:\/\/afsbio.com\/products\/pkm2-polyclonal-antibody-bt-ap07236","provider":"AFSBio Inc.","version":"1.0","type":"link"}