{"product_id":"plagl1-monoclonal-antibody-bt-mca3277","title":"PLAGL1 Monoclonal Antibody - BT-MCA3277","description":"\u003cp\u003ePLAGL1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3277-50, BT-MCA3277-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLAGL1\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8F9D12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PLAGL1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 50.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9UM63\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ZAC, LOT1, ZAC1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5325\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238424502451,"sku":"BT-MCA3277-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238424535219,"sku":"BT-MCA3277-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_6a3cdf01-bba9-4f61-b146-f359f3321dca.png?v=1769380568","url":"https:\/\/afsbio.com\/products\/plagl1-monoclonal-antibody-bt-mca3277","provider":"AFSBio Inc.","version":"1.0","type":"link"}