{"product_id":"plakophilin-2-rabbit-pab-es3232","title":"Plakophilin 2 rabbit pAb - ES3232","description":"\u003cp\u003ePlakophilin 2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3232-50, ES3232-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PKP2; Plakophilin-2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 97kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5318\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q99959\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cell junction, desmosome. Nuclear and associated with desmosomes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202122899635,"sku":"ES3232-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202122932403,"sku":"ES3232-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a96d3bad-135b-450a-a30f-0ad8342b0304.png?v=1767122441","url":"https:\/\/afsbio.com\/products\/plakophilin-2-rabbit-pab-es3232","provider":"AFSBio Inc.","version":"1.0","type":"link"}