{"product_id":"plasminogen-receptor-polyclonal-antibody-ra28862","title":"Plasminogen receptor Polyclonal Antibody - RA28862","description":"\u003cp\u003ePlasminogen receptor Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28862-50, RA28862-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.\u003c\/p\u003e \n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000, ELISA 1:10000-20000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Plasminogen receptor (KT) (Plg-R (KT))\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 55848\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 17\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9HBL7\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122369093811,"sku":"RA28862-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122369126579,"sku":"RA28862-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_90693466-2508-4719-a9f0-b52e840f7d6b.png?v=1773348080","url":"https:\/\/afsbio.com\/products\/plasminogen-receptor-polyclonal-antibody-ra28862","provider":"AFSBio Inc.","version":"1.0","type":"link"}