{"product_id":"plau-monoclonal-antibody-bt-mca3959","title":"PLAU Monoclonal Antibody - BT-MCA3959","description":"\u003cp\u003ePLAU Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3959-50, BT-MCA3959-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLAU\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6B6A3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PLAU\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PLAU (AA: 107-379) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 48.5KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P00749\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATF, QPD, UPA, URK, u-PA, BDPLT5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5328\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238520774835,"sku":"BT-MCA3959-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238520807603,"sku":"BT-MCA3959-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_46a7c1f4-2aaa-4d0b-a647-4c78469ca704.png?v=1769382108","url":"https:\/\/afsbio.com\/products\/plau-monoclonal-antibody-bt-mca3959","provider":"AFSBio Inc.","version":"1.0","type":"link"}