{"product_id":"plc-β2-rabbit-pab-es6603","title":"PLC β2 rabbit pAb - ES6603","description":"\u003cp\u003ePLC β2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6603-50, ES6603-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate + H (2)O = 1D-myo-inositol 1, 4, 5-trisphosphate + diacylglycerol., cofactor:Binds 1 calcium ion per subunit., function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes., miscellaneous:The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16., similarity:Contains 1 C2 domain., similarity:Contains 1 PI-PLC X-box domain., similarity:Contains 1 PI-PLC Y-box domain., subunit:Interacts with RAC1.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PLCB2; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from the Internal region of human PLC β2.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 150kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5330\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q00722\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: intracellular, cytosol,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202305351859,"sku":"ES6603-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202305384627,"sku":"ES6603-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3b5b9d7e-9972-4ac9-9fe8-3d7a4db7e077.png?v=1767126181","url":"https:\/\/afsbio.com\/products\/plc-%ce%b22-rabbit-pab-es6603","provider":"AFSBio Inc.","version":"1.0","type":"link"}