{"product_id":"plcd1-polyclonal-antibody-bt-ap13167","title":"PLCD1 Polyclonal Antibody - BT-AP13167","description":"\u003cp\u003ePLCD1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13167-20, BT-AP13167-50, BT-AP13167-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLCD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P51178; Mouse: Q8R3B1; Rat: P10688\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1;EC 3.1.4.11;Phosphoinositide phospholipase C-delta-1;Phospholipase C-III;PLC-III;Phospholipase C-delta-1;PLC-delta-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5333\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239290986675,"sku":"BT-AP13167-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239291019443,"sku":"BT-AP13167-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239291052211,"sku":"BT-AP13167-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e5640435-6e38-4c98-bdc7-50ad2316079f.png?v=1769392597","url":"https:\/\/afsbio.com\/products\/plcd1-polyclonal-antibody-bt-ap13167","provider":"AFSBio Inc.","version":"1.0","type":"link"}