{"product_id":"plcg2-monoclonal-antibody-bt-mca2036","title":"PLCG2 Monoclonal Antibody - BT-MCA2036","description":"\u003cp\u003ePLCG2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2036-50, BT-MCA2036-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLCG2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A8B6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PLCG2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)).\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 148kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P16885\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FCAS3, APLAID, PLC-IV, PLC-gamma-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5336\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238560030899,"sku":"BT-MCA2036-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238560063667,"sku":"BT-MCA2036-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_70ac2a02-a9c1-48f8-a6ca-f1b46491ac72.png?v=1769382569","url":"https:\/\/afsbio.com\/products\/plcg2-monoclonal-antibody-bt-mca2036","provider":"AFSBio Inc.","version":"1.0","type":"link"}