{"product_id":"plcl1-polyclonal-antibody-e-ab-91107","title":"PLCL1 Polyclonal Antibody - E-AB-91107","description":"\u003cp\u003ePLCL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91107-60, E-AB-91107-120, E-AB-91107-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PLCL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PLCL1; PLCE; PLCL; PLDL1; PPP1R127; PRIP\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15111\u003c\/p\u003e\n\n\u003cp\u003eBackground: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4, 5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PLCL1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 113kDa\/122kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 140kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146590519475,"sku":"E-AB-91107-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146590552243,"sku":"E-AB-91107-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146590585011,"sku":"E-AB-91107-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0fb5ae7e-fc8c-4879-a027-bc470176bd72.png?v=1710297985","url":"https:\/\/afsbio.com\/products\/plcl1-polyclonal-antibody-e-ab-91107","provider":"AFSBio Inc.","version":"1.0","type":"link"}