{"product_id":"plod2-mouse-monoclonal-antibody-mb4012","title":"PLOD2 Mouse Monoclonal Antibody - MB4012","description":"\u003cp\u003ePLOD2 Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB4012-25, MB4012-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticμlum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resμltant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecμlar crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2, EC:1.14.11.4 , Lysyl hydroxylase 2 (LH2), PLOD2\u003c\/p\u003e \n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Human recombinant protein fragment corresponding to amino acids 359-640 of human PLOD2 (NP_891988) produced in E.coli.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O00469\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"25μl","offer_id":45945961611443,"sku":"MB4012-25","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45945961644211,"sku":"MB4012-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/plod2-mouse-monoclonal-antibody-mb4012","provider":"AFSBio Inc.","version":"1.0","type":"link"}