{"product_id":"plod2-polyclonal-antibody-bt-ap13181","title":"PLOD2 Polyclonal Antibody - BT-AP13181","description":"\u003cp\u003ePLOD2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13181-20, BT-AP13181-50, BT-AP13181-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLOD2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O00469; Mouse: Q9R0B9; Rat: Q811A3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2;EC 1.14.11.4;Lysyl hydroxylase 2;LH2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5352\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239292035251,"sku":"BT-AP13181-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239292068019,"sku":"BT-AP13181-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239292100787,"sku":"BT-AP13181-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_662bd51b-5f67-4993-af28-ea25509a57eb.png?v=1769392611","url":"https:\/\/afsbio.com\/products\/plod2-polyclonal-antibody-bt-ap13181","provider":"AFSBio Inc.","version":"1.0","type":"link"}