{"product_id":"pls1-polyclonal-antibody-bt-ap13182","title":"PLS1 Polyclonal Antibody - BT-AP13182","description":"\u003cp\u003ePLS1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13182-20, BT-AP13182-50, BT-AP13182-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: cofactor:Calcium.,May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.,May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.,induction:By phosphorylation by PKC. Induced by INFB1 in response to a viral infection.,online information:Scramblase entry,PTM:Known to be palmitoylated at one, yet undefined, site.,Belongs to the phospholipid scramblase family.,subunit:Interacts with ABL.,tissue specificity:Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.,\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular; Microbiology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLSCR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospholipid scramblase 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O15162; Mouse: Q9JJ00; Rat: P58195\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Phospholipid scramblase 1;PL scramblase 1;Ca;2+-dependent phospholipid scramblase 1;Erythrocyte phospholipid scramblase;MmTRA1b\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5359\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239292133555,"sku":"BT-AP13182-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239292166323,"sku":"BT-AP13182-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239292199091,"sku":"BT-AP13182-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b2c165b9-0aa1-410d-bb96-8b3c6656aeae.png?v=1769392612","url":"https:\/\/afsbio.com\/products\/pls1-polyclonal-antibody-bt-ap13182","provider":"AFSBio Inc.","version":"1.0","type":"link"}