{"product_id":"pmel-monoclonal-antibody-bt-mca2982","title":"PMEL Monoclonal Antibody - BT-MCA2982","description":"\u003cp\u003ePMEL Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2982-50, BT-MCA2982-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PMEL\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5C6G8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PMEL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PMEL (AA: 25-192) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 70.2kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P40967\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: P1, SI, SIL, ME20, P100, SILV, ME20M, gp100, ME20-M, PMEL17, D12S53E\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6490\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238379544755,"sku":"BT-MCA2982-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238379577523,"sku":"BT-MCA2982-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8d205f26-7e58-41e6-a960-86f08655cc06.png?v=1769379533","url":"https:\/\/afsbio.com\/products\/pmel-monoclonal-antibody-bt-mca2982","provider":"AFSBio Inc.","version":"1.0","type":"link"}