{"product_id":"pms1-polyclonal-antibody-bt-ap07300","title":"PMS1 Polyclonal Antibody - BT-AP07300","description":"\u003cp\u003ePMS1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07300-20, BT-AP07300-50, BT-AP07300-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: PMS1 encodes a protein belonging to the DNA mismatch repair mutL\/hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PMS1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PMS1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 105830\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P54277\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5378\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239845912755,"sku":"BT-AP07300-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239845945523,"sku":"BT-AP07300-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239845978291,"sku":"BT-AP07300-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2a7850ea-d5d2-4790-9123-0b3c381fac60.png?v=1769399907","url":"https:\/\/afsbio.com\/products\/pms1-polyclonal-antibody-bt-ap07300","provider":"AFSBio Inc.","version":"1.0","type":"link"}