{"product_id":"pmvk-polyclonal-antibody-bt-ap13202","title":"PMVK Polyclonal Antibody - BT-AP13202","description":"\u003cp\u003ePMVK Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13202-20, BT-AP13202-50, BT-AP13202-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: PMVK\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phosphomevalonate kinase\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15126; Mouse: Q9D1G2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Phosphomevalonate kinase;PMKase;hPMK;EC 2.7.4.2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 10654\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239293509811,"sku":"BT-AP13202-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239293542579,"sku":"BT-AP13202-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239293575347,"sku":"BT-AP13202-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9bcdef92-e632-42b6-9502-f38670c8af6f.png?v=1769392636","url":"https:\/\/afsbio.com\/products\/pmvk-polyclonal-antibody-bt-ap13202","provider":"AFSBio Inc.","version":"1.0","type":"link"}