{"product_id":"pnpo-polyclonal-antibody-e-ab-67361","title":"PNPO Polyclonal Antibody - E-AB-67361","description":"\u003cp\u003ePNPO Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67361-60, E-AB-67361-120, E-AB-67361-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PNPO\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HEL-S-302; PDXPO; PNPO\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism, Neuroscience, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9NVS9\u003c\/p\u003e\n\n\u003cp\u003eBackground: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human PNPO.\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135890096307,"sku":"E-AB-67361-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135890129075,"sku":"E-AB-67361-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135890161843,"sku":"E-AB-67361-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ab5f0384-07ec-4cdd-8a4c-980b314f0620.png?v=1709985962","url":"https:\/\/afsbio.com\/products\/pnpo-polyclonal-antibody-e-ab-67361","provider":"AFSBio Inc.","version":"1.0","type":"link"}