{"product_id":"polk-polyclonal-antibody-e-ab-67725","title":"POLK Polyclonal Antibody - E-AB-67725","description":"\u003cp\u003ePOLK Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67725-60, E-AB-67725-120, E-AB-67725-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: POLK\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: POLK; DINB1; DINP; POLQ\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UBT6\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human POLK\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42kDa\/52kDa\/54kDa\/55kDa\/76kDa\/88kDa\/98kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 80kDa\/110kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146454728883,"sku":"E-AB-67725-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146454761651,"sku":"E-AB-67725-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146454794419,"sku":"E-AB-67725-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5110297f-ba76-4eff-a34d-17a11b286aeb.png?v=1710295872","url":"https:\/\/afsbio.com\/products\/polk-polyclonal-antibody-e-ab-67725","provider":"AFSBio Inc.","version":"1.0","type":"link"}