{"product_id":"polr2a-monoclonal-antibody-bt-mca4834","title":"POLR2A Monoclonal Antibody - BT-MCA4834","description":"\u003cp\u003ePOLR2A Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4834-50, BT-MCA4834-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: POLR2A\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1B1D8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: POLR2A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human POLR2A (AA: 128-258) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 217kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P24928\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5430\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238408609971,"sku":"BT-MCA4834-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238408642739,"sku":"BT-MCA4834-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b296c6ed-f7ae-479c-a4b6-b551ba69abd4.png?v=1769380191","url":"https:\/\/afsbio.com\/products\/polr2a-monoclonal-antibody-bt-mca4834","provider":"AFSBio Inc.","version":"1.0","type":"link"}