{"product_id":"porim-polyclonal-antibody-bt-ap13230","title":"PORIM Polyclonal Antibody - BT-AP13230","description":"\u003cp\u003ePORIM Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13230-20, BT-AP13230-50, BT-AP13230-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Tags and cell markers; Metabolism; Cancer; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TMEM123\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Porimin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8N131; Mouse: Q91Z22; Rat: Q5HZB0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Porimin;Keratinocytes-associated transmembrane protein 3;KCT-3;Pro-oncosis receptor inducing membrane injury;Transmembrane protein 123\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 114908\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239294918835,"sku":"BT-AP13230-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239294951603,"sku":"BT-AP13230-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239294984371,"sku":"BT-AP13230-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ce7cf2c1-dbdc-4611-a8e6-eca2f3ea8ae1.png?v=1769392657","url":"https:\/\/afsbio.com\/products\/porim-polyclonal-antibody-bt-ap13230","provider":"AFSBio Inc.","version":"1.0","type":"link"}