{"product_id":"pot1-polyclonal-antibody-bt-ap07334","title":"POT1 Polyclonal Antibody - BT-AP07334","description":"\u003cp\u003ePOT1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07334-20, BT-AP07334-50, BT-AP07334-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: POT1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: POT1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 71442\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NUX5; Mouse: Q91WC1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 25913\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239848173747,"sku":"BT-AP07334-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239848206515,"sku":"BT-AP07334-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239848239283,"sku":"BT-AP07334-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ef2cc063-cd1d-48aa-881d-8708b3a162dd.png?v=1769399939","url":"https:\/\/afsbio.com\/products\/pot1-polyclonal-antibody-bt-ap07334","provider":"AFSBio Inc.","version":"1.0","type":"link"}