{"product_id":"pou2af1-polyclonal-antibody-e-ab-61304","title":"POU2AF1 Polyclonal Antibody - E-AB-61304","description":"\u003cp\u003ePOU2AF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61304-60, E-AB-61304-120, E-AB-61304-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: POU2AF1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: POU2AF1; BOB1; OBF-1; OBF1; OCAB\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling,Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q16633\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transcriptional coactivator that specifically associates with either POU2F1\/OCT1 or POU2F2\/OCT2. It boosts the POU2F1\/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2\/OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of POU2F1\/OCT1 and POU2F2\/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2\/OCT2 coactivator (By similarity.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human POU2AF1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 27kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146159980723,"sku":"E-AB-61304-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146160013491,"sku":"E-AB-61304-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146160046259,"sku":"E-AB-61304-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_76f445ba-e522-49bc-bde4-ecd357ce9513.png?v=1710291378","url":"https:\/\/afsbio.com\/products\/pou2af1-polyclonal-antibody-e-ab-61304","provider":"AFSBio Inc.","version":"1.0","type":"link"}