{"product_id":"pp2a-aβ-pr65β-ppp2r1b-rabbit-pab-a24836","title":"PP2A-Aβ\/PR65β\/PPP2R1B Rabbit pAb - A24836","description":"\u003cp\u003ePP2A-Aβ\/PR65β\/PPP2R1B Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24836-20, A24836-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser\/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 52kDa\/61kDa\/66kDa\/73kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 66kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5519\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P30154\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: PPP2R1B; PP2A-Abeta; PR65B; protein phosphatase 2 scaffold subunit Abeta; PP2A-Aβ\/PR65β\/PPP2R1B\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Kinase, Cell Biology \u0026amp; Developmental Biology, Apoptosis, Cell Cycle, Centromere, Wnt\/β-Catenin Signaling Pathway.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: PPP2R1B\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189857837235,"sku":"A24836-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189857870003,"sku":"A24836-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2c22cfbf-dec0-4091-87f6-187e8118b851.png?v=1766436894","url":"https:\/\/afsbio.com\/products\/pp2a-a%ce%b2-pr65%ce%b2-ppp2r1b-rabbit-pab-a24836","provider":"AFSBio Inc.","version":"1.0","type":"link"}