{"product_id":"pp2a-aβ-rabbit-pab-es3247","title":"PP2A-Aβ rabbit pAb - ES3247","description":"\u003cp\u003ePP2A-Aβ rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3247-50, ES3247-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser\/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: PPP2R1B; Serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000.IHC-p:1:50-300 ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human PPP2R1B. AA range:552-601\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 66kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5519\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P30154\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: membrane raft, extracellular exosome,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202123686067,"sku":"ES3247-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202123718835,"sku":"ES3247-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_1905db6d-6f9e-4d0a-a3d4-d9ad264fc7f5.png?v=1767122466","url":"https:\/\/afsbio.com\/products\/pp2a-a%ce%b2-rabbit-pab-es3247","provider":"AFSBio Inc.","version":"1.0","type":"link"}