{"product_id":"ppar-α-phospho-ser21-rabbit-pab-es20158","title":"PPAR α (Phospho Ser21) rabbit pAb - ES20158","description":"\u003cp\u003ePPAR α (Phospho Ser21) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20158-50, ES20158-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids., online information:Peroxisome proliferator-activated receptor entry, similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain., subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13., tissue specificity:Skeletal muscle, liver, heart and kidney.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human PPAR α (Phospho Ser21)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 52kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5465\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q07869\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202428100787,"sku":"ES20158-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202428133555,"sku":"ES20158-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_f9265fa2-5b8c-4ac5-8a2a-178068fddb63.png?v=1767128993","url":"https:\/\/afsbio.com\/products\/ppar-%ce%b1-phospho-ser21-rabbit-pab-es20158","provider":"AFSBio Inc.","version":"1.0","type":"link"}