{"product_id":"ppgb-20k-cleaved-met327-rabbit-pab-es20021","title":"PPGB (20k, Cleaved-Met327) rabbit pAb - ES20021","description":"\u003cp\u003ePPGB (20k, Cleaved-Met327) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20021-50, ES20021-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:Release of a C-terminal amino acid with broad specificity., disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease., function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins., similarity:Belongs to the peptidase S10 family., subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Lysosomal protective protein (EC 3.4.16.5; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 20 52kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5476\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P10619\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Lysosome.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202425839795,"sku":"ES20021-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202425872563,"sku":"ES20021-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_6328cf80-a08b-4467-ab15-8d3bec3360f6.png?v=1767128938","url":"https:\/\/afsbio.com\/products\/ppgb-20k-cleaved-met327-rabbit-pab-es20021","provider":"AFSBio Inc.","version":"1.0","type":"link"}